Nicotine Replacement therapy

Nicotine Replacement therapy
Assessment Description
Joe is a 68-year-old Caucasian male who presents for assistance with tobacco cessation. He began smoking when he was 12 years old. He smoked 2 packs per day until last year when he began reducing the number of cigarettes he smokes per day. He is currently at 8 cigarettes per day. He smokes when he gets up in the morning, with coffee, after breakfast, midmorning, after lunch, midafternoon, after supper, and before bed. He states that the cigarettes help him focus. He describes that abrupt cessation creates increased craving, irritability, increased hunger, and anxiety.

Select a Nicotine replacement therapy or medication that is used for nicotine dependence. Please include the available evidence and treatment guidelines. Share the mechanism of action of this medication and hints for monitoring, side effects, and drug interactions, including interactions with CAM. Identify an additional (possibly off-labeled) use of the medication not related to depression or psychosis. Include the name of the medication in the subject line so that the medications can be followed. Include references using APA format.
Nicotine Replacement therapy


Due Date

In Joe’s case, Chantix (Varenicline) would be appropriate. Chantix is a pill that binds to the nicotine receptors in one’s brain. In a nutshell, Chantix attaches to one’s nicotine receptors in the brain so that nicotine cannot work (Jordan & Xi, 2018). It is critical to highlight that with Chantix; dopamine is released but minimal with nicotine. It is thus believed that such actions are how Chantix aids one in quitting smoking. This drug prevents nicotine cravings, much like nicotine replacement therapy. Also, Chantix is one of the most effective treatments that aid smokers quit.
Chantix is approximately three times as suitable and effective as a placebo for three months and one year. Also, based on the quit criterion, one may take Chantix for 12 or 24 weeks, that is, 3 or 6 months (Murray et al., 2022). During the first three months, most people using Chantix can quit smoking. However, it is essential to note that one cannot take Chantix when utilizing other medications to help seize smoking. Using Chantix and a nicotine patch leads to vomiting, nausea, stomach upsets, headaches, tiredness, and dizziness compared to using a nicotine patch alone.
There are side effects that could bother the user and do not go away hence the need to seek medical attention from a healthcare professional. Off-label Chantix leads to sleep problems such as trouble sleeping, strange and unusual dreams, vomiting or gas, and constipation (Giulietti et al., 2020). Other effects could be severe allergic reactions, which are rare, but seeking help from a medical practitioner is crucial. Allergic reactions may include swelling/itching mainly on the face, throat, and tongue, rashes, difficulties in breathing, and severe dizziness.

Giulietti, F., Filipponi, A., Rosettani, G., Giordano, P., Iacoacci, C., Spannella, F., & Sarzani, R. (2020). Pharmacological approach to smoking cessation: an updated review for daily clinical practice. High Blood Pressure & Cardiovascular Prevention, 27(5), 349-362.
Jordan, C. J., & Xi, Z. X. (2018). Discovery and development of varenicline for smoking cessation. Expert opinion on drug discovery, 13(7), 671-683.
Murray, R. L., Zhang, Y. Q., Ross, S., O’Brien, K. K., Zhu, M., Leone, F. T., … & Zhang, Y. (2022). Extended Duration Treatment of Tobacco Dependence: A Systematic Review. Annals of the American Thoracic Society, (ja).

Nicotine Replacement therapy

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